Research Roundup: Risk Assessment 1 (AIHce EXP 2022 OnDemand)
Course Description:
Recorded at AIHce EXP 2022

Presentations

Review of Solid and Liquid Loading Values on Skin — Applications for Risk Assessment, Part 1

Dermal exposure has been described as a complex process regarding the contact and interaction of substances with the skin surface over time. In 2018, 25,000 recordable skin diseases were reported by the U.S. Bureau of Labor Statistics (BLS), compared to 19,600 respiratory illnesses. Dermal exposures are not as well characterized as inhalation exposures. For solids, a key parameter of dermal exposure is the mass that contacts or loads onto the skin per square surface area. A literature review was conducted to identify and summarize available dermal solid loading measurements, as well as the key factors which may influence loading of solids on the skin surface. Our findings indicate that dermal loading quantities and patterns can be complex to assess. Default dermal loading values used in many dermal exposure models can differ significantly from measured values for some exposure scenarios, often overestimating exposure. This presentation will help attendees identify the available dermal loading measurements in the literature, understand the advantages and disadvantages of available measurements, and evaluate whether existing models or measurement data could be applicable to their scenario of interest.

Review of Solid and Liquid Loading Values on Skin — Applications for Risk Assessment, Part 2
Dermal exposure has been described as a complex process regarding the contact and interaction of substances with the skin surface over time. In 2018, 25,000 recordable skin diseases were reported by the U.S. Bureau of Labor Statistics (BLS), compared to 19,600 respiratory illnesses. Dermal exposures are not as well characterized as inhalation exposures. For liquids, a key parameter of dermal exposure is the volume or mass of liquid that contacts or loads onto the skin. A literature review was conducted to identify and summarize available dermal liquid loading measurements. The findings from this literature review highlight the relatively few scenarios and liquid substances for which dermal loading has been evaluated. Limitations of the available measurement methods often complicate the interpretation of measured dermal loading values. Further, our findings indicate that default dermal loading values used in many dermal exposure models can differ significantly from measured values for some exposure scenarios, often overestimating and in some cases underestimating exposure. This presentation will help attendees identify the available dermal loading measurements, understand the advantages and disadvantages of measurement methods used, and evaluate whether existing models or measurement data could be applicable to their scenario of interest.

Presentation Date:
05/23/2022

Presenters:
Nadia H Moore, PhD, DABT, CIH, ERT
Jennifer Sahmel, MPH, CIH, CSP, FAIHA
Heather Avens, PhD, MS, CIH

Session recordings are available for 90 days from purchase.


Stock #: AOD22_A1
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