Today’s widespread use of computers in an office setting has created a cluster of ergonomic conditions somewhat distinct from other workplace concerns. This guide addresses these conditions and will familiarize those who design office space, those who work in offices, and those responsible for the health and safety of office workers with ergonomic principles intended to minimize the risk of eyestrain, cumulative trauma disorders, and stress. Included is a quick checklist with possible interventions and other resources for workstation-related ergonomic safety.