The use of radiation in research, medicine, and industry is highly regulated. Safety professionals working with radiation must possess not only a good understanding of science, but also of regulatory requirements. The RSO Survival Handbook provides an introduction to radiation safety including basic radiation science, radiation safety practices and procedures, and federal or state regulations. References and examples of forms to be used for surveys, audits, or for other specific investigations are included. The information provided in this reference will benefit the RSO working in an academic, research, or medical facility.